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| | Homology Protein Modeling |
| | Analysis of the α-mannosidosis associated mutations in the human MAN2B1 homology model. In all figures the polypeptide is coloured according to the bovine MAN2B1 proteolytic segments: The N-terminal active site barrel is in red, peptides ‘b’, and ‘c’ forming the three helix bundle and first small β-domain are in orange and yellow, the large β-domain ‘d’ in green and the last ‘e’-peptide domain in blue. The figure of the overall MAN2B1 fold shows the site of the mutation in the MAN2B1 structure. In the detailed picture, the mutated, new residue is in white and the wild type residue in colour. |
| | ( Unpublished ) |
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